BARCELONA, SPAIN - MARCH 08: Lionel Messi,Sergio Roberto and Luis Suarez of Barcelona celebrate on the final whistle during the UEFA Champions League Round of 16 second leg match between FC Barcelona and Paris Saint-Germain at Camp Nou on March 8, 2017 in Barcelona, Spain.  (Photo by Laurence Griffiths/Getty Images)

6 of the Most Memorable Champions League Round of 16 Ties in History

Europe's most prestigious club competition is set to return, and after another enthralling Champions League group stage, we now get to the business end of matters with the commencement of the famous knockout rounds.

There are some star-studded matchups on the horizon, with the likes of cup holders Real Madrid battling it out with hot favourites Paris Saint-Germain and Antonio Conte's Chelsea looking to halt Lionel Messi and co. when they come up against Barcelona. 

The round of 16 has brought memorable touchline pandemonium, late Brazilian heroics and plenty of wonder goals to savour. 

On that note, we take a look at six of the most memorable Champions League last 16 ties in history:

6. Chelsea 5-4 Barcelona, 2004/05

After a 2-1 first-leg defeat at the Camp Nou in which Didier Drogba was sent off, Chelsea boss Mourinho accused Barca counterpart Frank Rijkaard of entering the referee’s room during half-time for a chat with referee Anders Frisk. 

This turned out to be merely a footnote in the drama that foresaw the events of the first-leg. In the second-leg at Stamford Bridge, Chelsea raced into a three-goal lead in 19 minutes, with Eidur Gudjohnsen, Frank Lampard and Damien Duff on target for Jose Mourinho's side.

But Barca pulled two goals back before half-time with Ronaldinho’s first coming from the penalty spot. His second goal has gone down as one of the most iconic goals in Champions League history as he showed sheer impudence, when he poked the ball with the outside of his boot beyond a jungle of players into the bottom corner.   

As it stood Chelsea were going out on away goals, but it was a John Terry header which sent the Blues through on a night which ended in chaos. After the acrimony surrounding the first leg, this clash also ended in controversy with Barcelona coach Frank Rijkaard having to be restrained as a fracas erupted near the tunnel.  

5. Manchester United 2-3 FC Porto, 2003/04

This was the tie that catapulted Jose Mourinho into global football consciousness as his Porto side knocked out Sir Alex Ferguson's Manchester United in their own backyard. 

Two Benni McCarthy goals helped Mourinho earn a 2-1 first-leg win, though it was in the return leg at Old Trafford where we saw the current Man Utd manager's infamous celebrations when he sprinted down the touchline celebrating a last minute goal. 

Paul Scholes' near post header after 31 minutes looked to have sent United through on away goals, but Costinha pounced as Tim Howard fumbled Benni McCarthy's free-kick to score in the 90th minute and silence Old Trafford. 

The win proved to be vital as it spurred them all the way to getting their hands on the Champions League trophy, beating AS Monaco 3-0 in the final.

4. Bayern Munich 3-3 Internazionale, 2010/11 (Inter win on away goals)

This repeat of the 2010 final promised much and did not fail to deliver. Inter came out on top in the final a year prior to this tie, beating Bayern 2-0 to complete the treble under Jose Mourinho.

It was the Bavarians who won the first-leg 1-0, but this proved to be of little convenience as Inter winning the reverse fixture 3-2, and ultimately went through on away goals.

Samuel Eto'o scored for Inter in the fourth minute, but Mario Gomez levelled in the 21st and Thomas Müller put Bayern ahead in the 31st minute. Wesley Sneijder scored just after the hour mark to pull Inter level, creating a tense and dramatic finale.

In the dying embers of the game,  Eto'o set up Goran Pandev with a neat pass and the Macedonian drove a left-foot shot into the roof of the net from inside the area. 

They couldn't emulate the success they had in the season prior however, as they were humiliated by German outfit Schalke 04, losing 7-3 on aggregate in the quarter finals.

3. Manchester City 6-6 AS Monaco, 2016/17 (AS Monaco Win on Away Goals)

Pep Guardiola's Manchester City side took a 5-3 lead from the first-leg at the Etihad and looked to have a foothold in the tie going into the reverse fixture in Monaco. 

However, the second-leg started just as the first finished, two attacking teams producing a see-saw thriller which saw Leonardo Jardim's youthful side take the victory via away goals.

Teenage sensation Kylian Mbappe opened the scoring through an excellent poked finish from close range. The Ligue 1 side - who at the time had already scored 123 goals in the season - doubled their advantage through Fabinho.

Guardiola's side were much improved in the second period, with Leroy Sane's strike putting City on course to qualify. However, it was Monaco's Tiemoue Bakayoko who decided the tie, as he headed home the decisive goal.

2. Bayern Munich 12-1 Sporting CP, 2008/09

This result is the biggest aggregate triumph in Champions League history.

Bayern Munich scored four goals in the second half of their first-leg match against Sporting CP to effectively kill off the tie. Franck Ribery gave the visitors the lead just before the half-time interval before the Bavarians exploded with four goals in the final 45 minutes to put the  Portuguese outfit in a big hole. 

The return fixture in Munich was just a show of relentless humiliation for the Portuguese side. The blitz carried over into the second-leg, with Lukas Podolski scoring in the eighth minute and by the end of the game, die Roten had emerged 7-1 victors. 

Six different goal scorers helped them equal the single-leg record for the largest winning margin in the knockout stage. 

1. Barcelona 6-5 Paris Saint-Germain, 2016/17

If you had to choose one game to act use an advert for the sport, it would have to be the encounter between two of European's giants going toe-to-toe with each other right up until the last.

The first-leg alone was an unfathomable brilliant spectacle to behold, as the Parisians came out 4-0 winners at the Stade de France, utterly humiliating Luis Enrique's team.

Then came the main event. If there was ever one team you'd back to overturn a four-goal deficit, it would have to be this Barca side who have the calibre of players that seem to be able to achieve the impossible.

Arguably the greatest comeback in Champions League history commenced after 40 minutes, when an own goal added to Luis Suárez's header to put the Catalonian side 2-0 up at the break. 

Lionel Messi then scored a penalty to get everybody believing that they will do the impossible, only for their hopes to be seemingly diminished by Edison Cavani, when he scored to make it 5-3 on aggregate.  

La Blaugrana now needed three goals to progress to the quarter finals and got two when Neymar went to work, reducing the deficit with a superb curling free-kick and a penalty kick.

Then five minutes into added time, an unlikely hero in Sergi Roberto was there to guide it home from a Neymar cross to spark wild celebrations from all the Barca faithful.